The Glycerin 22 is Brooks' premium cushioned daily trainer — built for runners who want a soft, smooth ride on every run, from easy recovery miles to long Sunday efforts. Nitrogen-infused DNA LOFT v3 cushioning delivers a plush underfoot feel without sacrificing responsiveness, while the streamlined upper wraps your foot in a secure, comfortable fit. If you log high mileage and want a shoe that keeps your legs feeling fresh, the Glycerin 22 belongs in your rotation.